Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14) (N-Term) Peptide
MAP3K14
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN979775
Quick Overview for Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14) (N-Term) Peptide (ABIN979775)
Target
MAP3K14
(Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- SEAGPAAISI IAQAECENSQ EFSPTFSERI FIAGSKQYSQ SESLDQIPNN
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MAP3K14 Antibody(ARP42161_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))
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Background
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This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.
Alias Symbols: FTDCR1B, HS, HSNIK, NIK
Protein Interaction Partner: CHUK,IKBKAP,IKBKB,TRAF1,TRAF2,TRAF3,TRAF5,TRAF6,ALPL,CASP8,CDC37,CHUK,EDAR,EGFR,FBL,GRB10,GRB14,GRB7,HSP90AA1,HSP90AB1,IKBKAP,IKBKB,IKBKG,MAP2K4,MAP3K14,MAP3K7,MAP3K8,MAPK3,NFKB2,PEBP1,PELI3,RIPK1,RPL30,RPL4,RPL5,RPL6,RPS11,RPS13,TRAF1,TRAF2,TRAF3,TRAF5,T
Protein Size: 947 -
Molecular Weight
- 104 kDa
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Gene ID
- 9020
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NCBI Accession
- NM_003954, NP_003945
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UniProt
- Q99558
Target
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