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Meis Homeobox 1 (MEIS1) (N-Term) Peptide

MEIS1 Reactivity: Human, Mouse Host: Synthetic BP, WB
Catalog No. ABIN979975

Quick Overview for Meis Homeobox 1 (MEIS1) (N-Term) Peptide (ABIN979975)

Target

MEIS1 (Meis Homeobox 1 (MEIS1))

Origin

Human, Mouse

Source

  • 6
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Sequence

    YGDPHAARSM QPVHHLNHGP PLHSHQYPHT AHTNAMAPSM GSSVNDALKR

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-Meis1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    MEIS1 (Meis Homeobox 1 (MEIS1))

    Background

    Meis1 acts as a transcriptional regulator of PAX6 and a transcriptional activator of PF4 in complex with PBX1 or PBX2. It is required for hematopoiesis, megakaryocyte lineage development and vascular patterning. It may function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias.

    Alias Symbols: C530044H18Rik, Evi8

    Protein Interaction Partner: Hoxa10,Hoxa11,Hoxa13,Hoxb13,Hoxc13,Hoxd12,Hoxd13,Pbx1,Pbx2,Pbx3,Pbx4,Pknox1,Tlx1

    Protein Size: 465

    Molecular Weight

    51 kDa

    Gene ID

    17268

    NCBI Accession

    NM_010789, NP_034919

    UniProt

    Q60954
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