Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) (Middle Region) Peptide
Quick Overview for Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) (Middle Region) Peptide (ABIN980085)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- PQYIAVHVVP DQLMAFGGSS EPCALCSLHS IGKIGGAQNR SYSKLLCGLL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MIF Antibody(ARP56347_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MIF (Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF))
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Background
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This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways.
Alias Symbols: GIF, GLIF, MMIF
Protein Interaction Partner: BNIPL,CD74,BNIPL,CD74,COPS5,COPS6,GORASP2,MIF,NME1,STRN4,TP53,ZNF408,BNIPL,CD74,COPS5,FIBP,GORASP2
Protein Size: 115 -
Molecular Weight
- 12 kDa
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Gene ID
- 4282
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NCBI Accession
- NM_002415, NP_002406
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UniProt
- P14174
Target
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