Melanophilin (MLPH) (C-Term) Peptide
MLPH
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Melanophilin (MLPH) products
- Melanophilin (MLPH)
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- NLPIFLPRVA GKLGKRPEDP NADPSSEAKA MAVPYLLRRK FSNSLKSQGK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MLPH Antibody(ARP59494_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Melanophilin (MLPH)
- Background
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This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Alias Symbols: MGC2771, MGC59733, SLAC2-A
Protein Interaction Partner: MYO5A,RAB27A,RAB27B,ACTA1,MYO5A,RAB10,RAB27A,RAB27B,RPH3A
Protein Size: 600 - Molecular Weight
- 66 kDa
- Gene ID
- 79083
- NCBI Accession
- NM_024101, NP_077006
- UniProt
- Q9BV36
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