Melatonin Receptor 1A (MTNR1A) (C-Term) Peptide
MTNR1A
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN980355
Quick Overview for Melatonin Receptor 1A (MTNR1A) (C-Term) Peptide (ABIN980355)
Target
Melatonin Receptor 1A (MTNR1A)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- GLLNQNFRKE YRRIIVSLCT ARVFFVDSSN DVADRVKWKP SPLMTNNNVV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MTNR1A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Melatonin Receptor 1A (MTNR1A) peptide
MTNR1A Reactivity: Human, Mouse, Cow, Dog Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Melatonin Receptor 1A (MTNR1A)
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Background
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This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
Alias Symbols: MEL-1A-R, MT1
Protein Interaction Partner: MTNR1A,MTNR1B,CALR,CANX,CNP,DPM1,EEF1G,FLNA,GNA11,GNA13,GNAI1,GNAI2,GNAI3,GNB1,GNB4,GPR50,HNRNPA0,HSPA5,IRS4,LRRC59,MTNR1A,MTNR1B,PDIA6,PGRMC1,RAB10,RAC1,RAP1A,TMEM33,VAPB,GNA11,GNAI2,GNAI3
Protein Size: 350 -
Molecular Weight
- 39 kDa
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Gene ID
- 4543
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NCBI Accession
- NM_005958, NP_005949
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UniProt
- P48039
Target
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