V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) Peptide
Quick Overview for V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) Peptide (ABIN980411)
Target
Origin
Source
Application
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MYBL2 antibody (Catalog #: P100748_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))
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Background
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Myb-Related Protein B (MYBL2), a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined.
Alias Symbols: BMYB, B-MYB
Protein Interaction Partner: E2F1,E2F2,E2F3,E2F4,RBL2,TTF2,CCNA1,CCNA2,CCND1,CCNE1,CDC34,CDK2,CDK9,CREBBP,EP300,LIN9,MYBL2,NCOR1,NCOR2,PARP1,RBL1,SKP2,SND1,TTF2,UBB,ZNF622,CCNA1,CCNT1,CDK2,CDK9,CDKN1C,CREBBP,E2F1,E2F3,EP300,MYBL2,PARP1,RBL1,SKP2,ZNF622
Protein Size: 700 -
Molecular Weight
- 79 kDa
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Gene ID
- 4605
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NCBI Accession
- NM_002466, NP_002457
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UniProt
- P10244
Target
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