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Non-SMC Condensin I Complex, Subunit D2 (NCAPD2) Peptide

NCAPD2 Reactivity: Human Host: Synthetic BP, WB

Catalog No. ABIN980515

Quick Overview for Non-SMC Condensin I Complex, Subunit D2 (NCAPD2) Peptide (ABIN980515)

Target

NCAPD2 (Non-SMC Condensin I Complex, Subunit D2 (NCAPD2))

Origin

Human

Source

Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)

Characteristics

This is a synthetic peptide designed for use in combination with anti-NCAPD2 antibody (Catalog #: ARP46210_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Purification

Purified
Non-SMC Condensin I Complex, Subunit D2 (NCAPD2) peptide
NCAPD2 Reactivity: Mammalian Host: Synthetic BP, WB, IHC

Application Notes

Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Concentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

NCAPD2 (Non-SMC Condensin I Complex, Subunit D2 (NCAPD2))

Background

NCAPD2 is the regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. NCAPD2 may target the condensin complex to DNA via its C-terminal domain.

Alias Symbols: CAP-D2, CNAP1, KIAA0159, hCAP-D2

Protein Interaction Partner: SMC2,SMC4,SMC2,SMC4

Protein Size: 1401

Molecular Weight

157 kDa

Gene ID

9918

NCBI Accession

NM_014865, NP_055680

UniProt

Q15021

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