Nerve Growth Factor Receptor (NGFR) (C-Term) Peptide
Quick Overview for Nerve Growth Factor Receptor (NGFR) (C-Term) Peptide (ABIN980695)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- VTRGTTDNLI PVYCSILAAV VVGLVAYIAF KRWNSCKQNK QGANSRPVNQ
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-NGFR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NGFR (Nerve Growth Factor Receptor (NGFR))
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Background
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Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain.
Alias Symbols: CD271, Gp80-LNGFR, TNFRSF16, p75(NTR), p75NTR
Protein Interaction Partner: LINGO1,NGF,NGF,NTF4,RTN4R,RTN4R,RTN4R,SORT1,TRADD,BEX1,CAV1,FSCN1,GRB2,IL2,KIDINS220,LINGO1,MAG,MAGED1,MAGEH1,MAPK1,MAPK3,NDN,NFKBIB,NGF,NGFRAP1,NTF4,NTRK1,NTRK2,NTRK3,PRKACB,PTPN13,RIPK2,RTN4R,SHC1,SORT1,TRA2B,TRADD,TRAF2,TRAF4,TRAF6,ZNF274,CAV1,FSCN1,MAGED1,MAGEH1,MYCN,NDN,NDNL2,NGF,NGFRAP1,PIAS2,PRKACB,SHC1,SP1,TCF19,TRADD,TRAF1,TRAF2,TRAF3,TRAF4,TRAF5,TRAF6,TRIM37
Protein Size: 427 -
Molecular Weight
- 47 kDa
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Gene ID
- 4804
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NCBI Accession
- NM_002507, NP_002498
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UniProt
- P08138
Target
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