Neuro-Oncological Ventral Antigen 1 (NOVA1) (Middle Region) Peptide
Quick Overview for Neuro-Oncological Ventral Antigen 1 (NOVA1) (Middle Region) Peptide (ABIN980818)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-NOVA1 antibody (Catalog #: ARP40398_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NOVA1 (Neuro-Oncological Ventral Antigen 1 (NOVA1))
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Background
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NOVA1 is a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.
Alias Symbols: Nova-1
Protein Interaction Partner: NOVA1,PCBP1,SMARCC2
Protein Size: 507 -
Molecular Weight
- 52 kDa
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Gene ID
- 4857
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NCBI Accession
- NM_002515, NP_002506
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UniProt
- A8K603
Target
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