Ornithine Aminotransferase (OAT) (Middle Region) Peptide
OAT
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981078
Quick Overview for Ornithine Aminotransferase (OAT) (Middle Region) Peptide (ABIN981078)
Target
OAT
(Ornithine Aminotransferase (OAT))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-OAT antibody (Catalog #: ARP48134_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Ornithine Aminotransferase (OAT) (AA 33-439) peptide
OAT Reactivity: Human Host: Escherichia coli (E. coli) SDS
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- OAT (Ornithine Aminotransferase (OAT))
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Background
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OAT is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme is the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-42 DB459793.1 27-68 43-2062 BC016928.1 1-2020 2063-2066 M12267.1 2010-2013
Alias Symbols: DKFZp781A11155, HOGA, OKT, GACR, OATASE
Protein Interaction Partner: C2orf18,OAT,UBQLN4,C2orf18,DMWD,EIF6,OTUD4
Protein Size: 439 -
Molecular Weight
- 45 kDa
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Gene ID
- 4942
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NCBI Accession
- NM_000274, NP_000265
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UniProt
- P04181
Target
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