Ornithine Decarboxylase Antizyme 3 (OAZ3) (Middle Region) Peptide
OAZ3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981081
Quick Overview for Ornithine Decarboxylase Antizyme 3 (OAZ3) (Middle Region) Peptide (ABIN981081)
Target
OAZ3
(Ornithine Decarboxylase Antizyme 3 (OAZ3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- DRRLFLDIPY QALDQGNRES LTATLEYVEE KTNVDSVFVN FQNDRNDRGA
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-OAZ3 Antibody(ARP53713_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- OAZ3 (Ornithine Decarboxylase Antizyme 3 (OAZ3))
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Background
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Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. In contrast to antizymes 1 and 2, which are widely expressed throughout the body, the expression of this gene product (antizyme 3) is restricted to testis germ cells, and thus it is a possible candidate for heritable forms of human male infertility. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AZ3, OAZ-t, TISP15
Protein Interaction Partner: GGN,OAZ1,SMAD1
Protein Size: 187 -
Molecular Weight
- 21 kDa
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Gene ID
- 51686
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NCBI Accession
- NM_016178, NP_057262
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UniProt
- Q9UMX2
Target
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