Peptidylglycine alpha-Amidating Monooxygenase (PAM) Peptide
PAM
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981324
Quick Overview for Peptidylglycine alpha-Amidating Monooxygenase (PAM) Peptide (ABIN981324)
Target
PAM
(Peptidylglycine alpha-Amidating Monooxygenase (PAM))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PAM antibody (Catalog #: ARP43512_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))
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Background
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PAM is a multifunctional protein. It has two enzymatically active domains with catalytic activities-peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products.This gene encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known.
Alias Symbols: PAL, PHM
Protein Interaction Partner: KALRN,PRKCA,RASSF9,TSC2,UHMK1,KALRN,RASSF9,TSC1,TSC2
Protein Size: 974 -
Molecular Weight
- 108 kDa
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Gene ID
- 5066
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NCBI Accession
- NM_000919, NP_000910
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UniProt
- A6NMR0
Target
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