Peptidylglycine alpha-Amidating Monooxygenase (PAM) Peptide
PAM
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PAM products
- PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PAM antibody (Catalog #: ARP43512_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))
- Background
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PAM is a multifunctional protein. It has two enzymatically active domains with catalytic activities-peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products.This gene encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known.
Alias Symbols: PAL, PHM
Protein Interaction Partner: KALRN,PRKCA,RASSF9,TSC2,UHMK1,KALRN,RASSF9,TSC1,TSC2
Protein Size: 974 - Molecular Weight
- 108 kDa
- Gene ID
- 5066
- NCBI Accession
- NM_000919, NP_000910
- UniProt
- A6NMR0
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