Par-6 Partitioning Defective 6 Homolog alpha (PARD6A) (N-Term) Peptide
PARD6A
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981349
Quick Overview for Par-6 Partitioning Defective 6 Homolog alpha (PARD6A) (N-Term) Peptide (ABIN981349)
Target
PARD6A
(Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- MARPQRTPAR SPDSIVEVKS KFDAEFRRFA LPRASVSGFQ EFSRLLRAVH
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PARD6A Antibody(ARP42883_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PARD6A (Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))
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Background
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This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: PAR-6A, PAR6, PAR6C, PAR6alpha, TAX40, TIP-40
Protein Interaction Partner: PLCB1,PLCB3,CDC42,CDH5,CRB3,ECT2,GLS,MAP2K5,MARK2,MARK4,PARD3,PARD6B,PLCB1,PLCB3,PRKCG,PRKCH,PRKCI,PRKCZ,RAC1,RHOQ,TCP10,TGFBR1,YWHAH,YWHAZ,CDC42,DGKZ,ECT2,MPP5,PARD3,PRKCI,PRKCZ,RAC1,RHOQ
Protein Size: 345 -
Molecular Weight
- 37 kDa
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Gene ID
- 50855
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NCBI Accession
- NM_001037281, NP_001032358
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UniProt
- Q3TY70
Target
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