Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16) Peptide
PARP16
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981362
Quick Overview for Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16) Peptide (ABIN981362)
Target
PARP16
(Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PARP16 antibody (Catalog #: ARP33751_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PARP16 (Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))
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Background
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Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. PARP16 is a member of poly(ADP-ribose) polymerases (PARPs) family that is encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death. Some of these new members interact with each other, share common partners and common subcellular localizations suggesting possible fine tuning in the regulation of this post-translational modification of proteins.
Alias Symbols: pART15, C15orf30
Protein Size: 323 -
Molecular Weight
- 36 kDa
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Gene ID
- 54956
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NCBI Accession
- NM_017851, NP_060321
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UniProt
- Q6PK64
Target
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