Poly (ADP-Ribose) Polymerase 2 (PARP2) Peptide
-
- Target See all PARP2 products
- PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunocytochemistry (ICC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PARP2 antibody (Catalog #: ARP33758_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))
- Background
-
PARP2 contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of protein.
Alias Symbols: ADPRT2, PARP-2, ADPRTL2, ADPRTL3, pADPRT-2
Protein Interaction Partner: BUB3,CASP8,CENPA,CENPB,PARP1,XRCC1,PARP1,XRCC1
Protein Size: 534 - Molecular Weight
- 61 kDa
- Gene ID
- 10038
- NCBI Accession
- NM_005484, NP_005475
- UniProt
- Q9UGN5
-