Poly (ADP-Ribose) Polymerase 2 (PARP2) Peptide
Quick Overview for Poly (ADP-Ribose) Polymerase 2 (PARP2) Peptide (ABIN981364)
Target
Origin
Source
Application
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PARP2 antibody (Catalog #: ARP33758_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))
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Background
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PARP2 contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of protein.
Alias Symbols: ADPRT2, PARP-2, ADPRTL2, ADPRTL3, pADPRT-2
Protein Interaction Partner: BUB3,CASP8,CENPA,CENPB,PARP1,XRCC1,PARP1,XRCC1
Protein Size: 534 -
Molecular Weight
- 61 kDa
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Gene ID
- 10038
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NCBI Accession
- NM_005484, NP_005475
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UniProt
- Q9UGN5
Target
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