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Poly (ADP-Ribose) Polymerase 2 (PARP2) Peptide

PARP2 Reactivity: Human Host: Synthetic BP, WB, ICC
Catalog No. ABIN981364

Quick Overview for Poly (ADP-Ribose) Polymerase 2 (PARP2) Peptide (ABIN981364)

Target

PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Origin

Human

Source

  • 4
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunocytochemistry (ICC)
  • Characteristics

    This is a synthetic peptide designed for use in combination with anti-PARP2 antibody (Catalog #: ARP33758_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

    Background

    PARP2 contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of protein.

    Alias Symbols: ADPRT2, PARP-2, ADPRTL2, ADPRTL3, pADPRT-2

    Protein Interaction Partner: BUB3,CASP8,CENPA,CENPB,PARP1,XRCC1,PARP1,XRCC1

    Protein Size: 534

    Molecular Weight

    61 kDa

    Gene ID

    10038

    NCBI Accession

    NM_005484, NP_005475

    UniProt

    Q9UGN5
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