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Paired Box Gene 2a (PAX2A) (Middle Region) Peptide

PAX2A Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN981382

Quick Overview for Paired Box Gene 2a (PAX2A) (Middle Region) Peptide (ABIN981382)

Target

PAX2A (Paired Box Gene 2a (PAX2A))

Origin

Human

Source

  • 7
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequence

    DPVGSYSING ILGIPRSNGE KRKRDEDVSE GSVPNGDSQS GVDSLRKHLR

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-PAX2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    PAX2A (Paired Box Gene 2a (PAX2A))

    Background

    PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia.

    Alias Symbols: -

    Protein Size: 393

    Molecular Weight

    42 kDa

    Gene ID

    5076

    NCBI Accession

    NM_000278, NP_000269

    UniProt

    Q02962
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