Poly(rC) Binding Protein 4 (PCBP4) Peptide
PCBP4
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981432
Quick Overview for Poly(rC) Binding Protein 4 (PCBP4) Peptide (ABIN981432)
Target
PCBP4
(Poly(rC) Binding Protein 4 (PCBP4))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PCBP4 antibody (Catalog #: ARP40944_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Poly(rC) Binding Protein 4 (PCBP4) peptide
PCBP4 Reactivity: Human, Dog, Mouse, Rat Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PCBP4 (Poly(rC) Binding Protein 4 (PCBP4))
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Background
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PCBP4 is a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M.This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined.
Alias Symbols: CBP, LIP4, MCG10
Protein Interaction Partner: A2BP1,PCBP1,QKI,RNF138,LYST
Protein Size: 424 -
Molecular Weight
- 47 kDa
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Gene ID
- 57060
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NCBI Accession
- NM_020418, NP_065151
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UniProt
- Q9GZT1
Target
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