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Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5) (Middle Region) Peptide

PCSK5 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN981482
  • Target See all PCSK5 products
    PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PCSK5 antibody (Catalog #: ARP43530_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))
    Background
    PCSK5 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. PCSK5 mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known.The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: PC5, PC6, PC6A, SPC6

    Protein Interaction Partner: AMH,APPBP2,ATN1,ITGA6,PMCH,PTPRM,REN,APPBP2

    Protein Size: 913
    Molecular Weight
    89 kDa
    Gene ID
    5125
    NCBI Accession
    NM_006200, NP_006191
    UniProt
    Q92824
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