Paternally Expressed 3 (PEG3) Peptide
PEG3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981577
Quick Overview for Paternally Expressed 3 (PEG3) Peptide (ABIN981577)
Target
PEG3
(Paternally Expressed 3 (PEG3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PEG3 antibody (Catalog #: ARP38756_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PEG3 (Paternally Expressed 3 (PEG3))
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Background
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PEG3 induces apoptosis in cooperation with SIAH1A and acts as a mediator between TP53/p53 and BAX in a neuronal death pathway that is activated by DNA damage. PEG3 acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B. PEG3 also possesses a tumor suppressing activity in glioma cells.
Alias Symbols: PW1, ZNF904, ZSCAN24
Protein Interaction Partner: SIAH1,SIAH2,TRAF2,USP7,BRCA1,SIAH1,SIAH2
Protein Size: 1588 -
Molecular Weight
- 181 kDa
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Gene ID
- 5178
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NCBI Accession
- NM_006210, NP_006201
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UniProt
- Q9GZU2
Target
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