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phosphofructokinase, Platelet (PFKP) (C-Term) Peptide

PFKP Reactivity: Human Host: Synthetic BP, WB

Catalog No. ABIN981621

Quick Overview for phosphofructokinase, Platelet (PFKP) (C-Term) Peptide (ABIN981621)

Target

PFKP (phosphofructokinase, Platelet (PFKP))

Origin

Human

Source

Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)

Protein Region

C-Term

Sequence

EWITAKLKEA RGRGKKFTTD DSICVLGISK RNVIFQPVAE LKKQTDFEHR

Characteristics

This is a synthetic peptide designed for use in combination with anti-PFKP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Purification

Purified
phosphofructokinase, Platelet (PFKP) peptide
PFKP Reactivity: Human, Monkey, Mouse, Rat Host: Synthetic BP

Application Notes

Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Concentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

PFKP (phosphofructokinase, Platelet (PFKP))

Background

The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM, MIM 610681) and liver (PFKL, MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.

Alias Symbols: FLJ40226, PFK-C, PFKF

Protein Interaction Partner: DYNLL1,DMWD,GBAS,MCC,UBC,WIPI2

Protein Size: 784

Molecular Weight

85 kDa

Gene ID

5214

NCBI Accession

NM_002627, NP_002618

UniProt

Q01813

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