Phospholipase D2 (PLD2) (N-Term) Peptide
PLD2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981845
Quick Overview for Phospholipase D2 (PLD2) (N-Term) Peptide (ABIN981845)
Target
Phospholipase D2 (PLD2)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PLD2 antibody (Catalog #: ARP38182_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Phospholipase D2 (PLD2)
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Background
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Phosphatidylcholine (PC)-specific phospholipases D (PLDs, EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.Phosphatidylcholine (PC)-specific phospholipases D (PLDs, EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-14 AF033850.1 61-74 15-614 BC015033.1 1-600 615-1279 BC056871.1 549-1213 1280-1830 BC015033.1 1266-1816 1831-1995 BC056871.1 1765-1929 1996-3489 BC015033.1 1982-3475
Alias Symbols: -
Protein Interaction Partner: EGFR,PLCG1,ACTB,ACTN1,ALDOA,ALDOC,AMPH,AQP3,ARF1,BIN1,CAV1,CSK,DPYSL2,EGFR,FYN,GAPDH,GM2A,LCK,MTOR,OPRM1,PEA15,PIP5K1A,PLCG1,PRKCA,PRKCD,RPTOR,STXBP1,ALDOA,AMPH,AQP3,ARF1,Actb,BIN1,CAV1,CAV2,EGFR,GAPDH,MTOR,OPRM1,PEA15,PLCG1,PRKCA,PRKCD,RPTOR,SRC
Protein Size: 933 -
Molecular Weight
- 106 kDa
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Gene ID
- 5338
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NCBI Accession
- NM_002663, NP_002654
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UniProt
- O14939
Target
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