Polymerase (RNA) II (DNA Directed) Polypeptide B, 140kDa (POLR2B) Peptide
POLR2B
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN981961
Quick Overview for Polymerase (RNA) II (DNA Directed) Polypeptide B, 140kDa (POLR2B) Peptide (ABIN981961)
Target
POLR2B
(Polymerase (RNA) II (DNA Directed) Polypeptide B, 140kDa (POLR2B))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-POLR2B antibody (Catalog #: ARP32456_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- POLR2B (Polymerase (RNA) II (DNA Directed) Polypeptide B, 140kDa (POLR2B))
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Background
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POLR2B encodes the second largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with at least two other polymerase subunits, forms a structure within the polymerase that maintains contact in the active site of the enzyme between the DNA template and the newly synthesized RNA.
Alias Symbols: RPB2, POL2RB, hsRPB2, hRPB140
Protein Interaction Partner: CTDP1,POLR2C,POLR2D,POLR2H,POLR2H,POLR2L,BTF3,CTDP1,MEN1,POLR2C,POLR2D,POLR2H,POLR2L,AIRE,BTF3,GPN1,GTF2F1,GTF2F2,KDM1A,MED10,MED19,MED26,MED28,MED29,MED9,POLR2C,POLR2E,POLR2G,POLR2H,POLR2J,POLR2K,POLR2L,RECQL5,RPAP1,RPAP2,RPAP3,RUVBL2,TCEA1
Protein Size: 1174 -
Molecular Weight
- 134 kDa
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Gene ID
- 5431
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NCBI Accession
- NM_000938, NP_000929
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UniProt
- P30876
Target
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