POU Class 3 Homeobox 2 (POU3F2) Peptide
POU3F2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all POU3F2 products
- POU3F2 (POU Class 3 Homeobox 2 (POU3F2))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-POU3F2 antibody (Catalog #: P100858_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- POU3F2 (POU Class 3 Homeobox 2 (POU3F2))
- Background
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N-Oct-3 (POU3F2) is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1) and Oct2 (POU2F2), and the pituitary protein Pit1 (PIT1). Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression. N-Oct-3 is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1, MIM 164175) and Oct2 (POU2F2, MIM 164176), and the pituitary protein Pit1 (PIT1, MIM 173110). Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression.[supplied by OMIM].
Alias Symbols: BRN2, OCT7, OTF7, OTF-7, POUF3, brn-2, oct-7
Protein Interaction Partner: EP300,GTF2B,PAX3,POU3F2,SOX10,TBP,EP300,GTF2B,POU3F2,POU3F4,PQBP1,SOX10,SOX11,TBP,POU3F4,PQBP1
Protein Size: 443 - Molecular Weight
- 47 kDa
- Gene ID
- 5454
- NCBI Accession
- NM_005604, NP_005595
- UniProt
- P20265
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