Protein Kinase A, alpha (PRKACA) (N-Term) Peptide
PRKACA
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN982208
$160.46
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100 μg
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Quick Overview for Protein Kinase A, alpha (PRKACA) (N-Term) Peptide (ABIN982208)
Target
PRKACA
(Protein Kinase A, alpha (PRKACA))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- MASNSSDVKE FLAKAKEDFL KKWESPAQNT AHLDQFERIK TLGTGSFGRV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PRKACA Antibody(ARP57828_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PRKACA (Protein Kinase A, alpha (PRKACA))
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Background
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CAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alias Symbols: MGC102831, MGC48865, PKACA
Protein Interaction Partner: NMT1,AANAT,ABCA1,ACCN2,ACLY,ADCY5,ADD1,ADD2,ADRBK1,AKAP14,AKAP8L,APC,ATF1,ATP2B1,AURKA,BAD,BCL2,BRAF,C11orf17,C7orf16,CACNA1C,CACNB2,CACNG2,CAD,CCND1,CDK16,CETN1,CFTR,CIITA,CLDN3,CREM,CSK,CUL5,DNAJC5,DSP,EEF2K,EGFR,EPB49,ESR1,ETV1,FOS,FXYD1,GABRR1,GFAP,GJ
Protein Size: 343 -
Molecular Weight
- 40 kDa
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Gene ID
- 5566
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NCBI Accession
- NM_207518, NP_997401
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UniProt
- A8K8B9
Target
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