Presenilin Enhancer 2 Homolog (PSENEN) (N-Term) Peptide
PSENEN
Reactivity: Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN982324
Quick Overview for Presenilin Enhancer 2 Homolog (PSENEN) (N-Term) Peptide (ABIN982324)
Target
PEN2 (PSENEN)
(Presenilin Enhancer 2 Homolog (PSENEN))
Origin
Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- LGGFAFLPFL WLVNIFWFFR EAFLAPAYTE QSQIKGYVWR SAVGFLFWVI
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Psenen Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))
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Background
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Psenen is an essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.
Alias Symbols: 1700023M09Rik, MGC102026
Protein Size: 101 -
Molecular Weight
- 12 kDa
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Gene ID
- 66340
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NCBI Accession
- NM_025498, NP_079774
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UniProt
- Q9CQR7
Target
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