Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8) Peptide
PSMD8
Reactivity: Human
Host: Synthetic
WB, BP
Catalog No. ABIN982388
Quick Overview for Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8) Peptide (ABIN982388)
Target
PSMD8
(Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8))
Origin
Human
Source
Synthetic
Application
Western Blotting (WB), Blocking Peptide (BP)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PSMD8 antibody (Catalog #: ARP48216_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8) peptide (Ovalbumin)
PSMD8 Reactivity: Human Host: Synthetic WB, Imm, SDS
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PSMD8 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8))
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Background
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. PSMD8 is a non-ATPase subunit of the 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.
Alias Symbols: HIP6, HYPF, MGC1660, Nin1p, Rpn12, S14, p31
Protein Interaction Partner: UCHL5,SMAD2,SMAD9,UCHL5,PAAF1,PSMD13,PSMD6,UCHL5
Protein Size: 257 -
Molecular Weight
- 27 kDa
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Gene ID
- 5714
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UniProt
- P48556
Target
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