Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3) (Middle Region) Peptide
PTP4A3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN982444
Quick Overview for Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3) (Middle Region) Peptide (ABIN982444)
Target
PTP4A3
(Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PTP4A3 antibody (Catalog #: ARP51193_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))
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Background
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PTP4A3 belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contains a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth.The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist.
Alias Symbols: PRL-3, PRL-R, PRL3
Protein Interaction Partner: FNTA,FNTB,ABCD3,AIFM1,ATAD3A,ATP1B3,ATP2A2,CDK2,CNNM3,FANCI,GCN1L1,GTF2I,HEATR1,HEATR2,HNRNPM,IPO4,KIAA0368,KIAA1279,LRPPRC,MCM3,MMS19,MSH2,NCAPG,NUP188,POLD1,PRPSAP1,PSMD3,RAB3GAP2,SMAP1,SMC2,SRPRB,TMEM33,TNPO2,TTC27,UBE4A,USO1,XPO5,XPO7
Protein Size: 173 -
Molecular Weight
- 19 kDa
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Gene ID
- 11156
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NCBI Accession
- NM_032611, NP_116000
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UniProt
- O75365
Target
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