Purine-Rich Element Binding Protein A (PURA) (N-Term) Peptide
PURA
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PURA products
- PURA (Purine-Rich Element Binding Protein A (PURA))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MADRDSGSEQ GGAALGSGGS LGHPGSGSGS GGGGGGGGGG GGSGGGGGGA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- PURA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PURA (Purine-Rich Element Binding Protein A (PURA))
- Background
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This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.
Alias Symbols: PUR1, MRD31, PURALPHA, PUR-ALPHA
Protein Size: 322 - Molecular Weight
- 35 kDa
- Gene ID
- 5813
- NCBI Accession
- NM_005859, NP_005850
- UniProt
- Q00577
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