RAD51 Homolog B (Rad51B) (Middle Region) Peptide
Rad51B
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN982611
Quick Overview for RAD51 Homolog B (Rad51B) (Middle Region) Peptide (ABIN982611)
Target
RAD51 Homolog B (Rad51B)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- TESAFSAERL VEIAESRFPR YFNTEEKLLL TSSKVHLYRE LTCDEVLQRI
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RAD51L1 Antibody(ARP57720_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RAD51 Homolog B (Rad51B)
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Background
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The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alias Symbols: MGC34245, R51H2, RAD51B, REC2, hREC2, RAD51L1
Protein Interaction Partner: H1F0,HIST1H2BG,HIST1H3A,HIST2H4A,RAD51C,RAD51L3,HIST1H1A,HIST3H2BB,HIST3H3,HIST4H4,RAD51,RAD51C,RAD51L3,XRCC2
Protein Size: 350 -
Molecular Weight
- 38 kDa
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Gene ID
- 5890
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NCBI Accession
- NM_133510, NP_598194
Target
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