Ran GTPase Activating Protein 1 (RANGAP1) (N-Term) Peptide
Quick Overview for Ran GTPase Activating Protein 1 (RANGAP1) (N-Term) Peptide (ABIN982646)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RANGAP1 antibody (Catalog #: ARP56509_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))
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Background
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RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGA
Alias Symbols: Fug1, KIAA1835, MGC20266, SD
Protein Interaction Partner: SUMO1,UBE2I,CSNK2A1,IPO8,RAN,RANBP2,RANGAP1,SUMO1,SUMO2,SUMO3,UBE2I,C19orf62,GSP1,MEPCE,PMS1,RAN,RANGAP1,SIZ1,SUMO1,Senp2,UBE2I
Protein Size: 587 -
Molecular Weight
- 63 kDa
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Gene ID
- 5905
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NCBI Accession
- NM_002883, NP_002874
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UniProt
- P46060
Target
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