RAS Protein Activator Like 1 (GAP1 Like) (RASAL1) (C-Term) Peptide
RASAL1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RASAL1 products
- RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DTTLEADTGA CPEVLARQRA ATARLLEVLA DLDRAHEEFQ QQERGKAALG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RASAL1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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RAS Protein Activator Like 1 (GAP1 Like) (RASAL1) peptide
RASAL1 Reactivity: Human Host: Synthetic BP, Imm
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))
- Background
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The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described.
Alias Symbols: RASAL
Protein Interaction Partner: PITX1
Protein Size: 804 - Molecular Weight
- 88 kDa
- Gene ID
- 8437
- NCBI Accession
- NM_004658, NP_004649
- UniProt
- O95294
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