Regulator of G-Protein Signalling 18 (RGS18) (Middle Region) Peptide
RGS18
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN982926
Quick Overview for Regulator of G-Protein Signalling 18 (RGS18) (Middle Region) Peptide (ABIN982926)
Target
RGS18
(Regulator of G-Protein Signalling 18 (RGS18))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- EDFKKSKGPQ QIHLKAKAIY EKFIQTDAPK EVNLDFHTKE VITNSITQPT
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RGS18 Antibody(ARP42805_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Regulator of G-Protein Signalling 18 (RGS18) peptide
RGS18 Reactivity: Human Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RGS18 (Regulator of G-Protein Signalling 18 (RGS18))
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Background
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RGS18 is a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
Alias Symbols: RGS13
Protein Interaction Partner: GNAI1,GNAI2,GNAI3,GNAQ,GNAI1,GNAI2,GNAI3,GNAQ
Protein Size: 235 -
Molecular Weight
- 27 kDa
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Gene ID
- 64407
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NCBI Accession
- NM_130782, NP_570138
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UniProt
- Q9NS28
Target
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