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Rh Blood Group, D Antigen (RHD) (N-Term) Peptide

RHD Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN982955

Quick Overview for Rh Blood Group, D Antigen (RHD) (N-Term) Peptide (ABIN982955)

Target

RHD (Rh Blood Group, D Antigen (RHD))

Origin

Human

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Sequence

    WALTLEAALI LLFYFFTHYD ASLEDQKGLV ASYQVGQDLT VMAAIGLGFL

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-RHD Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    RHD (Rh Blood Group, D Antigen (RHD))

    Background

    The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: CD240D, DIIIc, MGC165007, RH, RH30, RHCED, RHDVA(TT), RHDel, RHPII, RHXIII, Rh4, RhDCw, RhII, RhK562-II, RhPI

    Protein Interaction Partner: BAZ1B

    Protein Size: 321

    Molecular Weight

    35 kDa

    Gene ID

    6007

    NCBI Accession

    NM_001127691, NP_001121163

    UniProt

    Q5XLT3
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