Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (Middle Region) Peptide
RIPK2
Reactivity: Human
Host: Synthetic
BP, WB, ICC
Catalog No. ABIN983001
Quick Overview for Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (Middle Region) Peptide (ABIN983001)
Target
RIPK2
(Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunocytochemistry (ICC)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RIPK2 antibody (Catalog #: AVARP02047_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))
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Background
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RIPK2 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. It contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CARD3, CARDIAK, CCK, GIG30, RICK, RIP2
Protein Interaction Partner: NOD1,NOD2,BCL10,BIRC3,CARD16,CARD6,CASP1,CASP8,CD40,CFLAR,IKBKG,IRAK1,NGFR,NOD1,NOD2,SMAD4,SMURF1,TLR2,TLR4,TNFRSF1A,TRAF1,TRAF2,TRAF5,TRAF6,UBE2I,BIRC2,BIRC3,CARD6,CASP1,CD40,CFLAR,COP,IKBKG,KCTD12,NOD1,NOD2,PHB2,RPL38,RPS14,TNFRSF1A,TRAF1,TRAF2,TRAF5,TRAF6,UBC,UBE2I
Protein Size: 540 -
Molecular Weight
- 61 kDa
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Gene ID
- 8767
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NCBI Accession
- NM_003821, NP_003812
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UniProt
- O43353
Target
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