RAR-Related Orphan Receptor A (RORA) (N-Term) Peptide
RORA
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN983127
Quick Overview for RAR-Related Orphan Receptor A (RORA) (N-Term) Peptide (ABIN983127)
Target
RORA
(RAR-Related Orphan Receptor A (RORA))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RORA antibody (Catalog #: ARP45642_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RORA (RAR-Related Orphan Receptor A (RORA))
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Background
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The protein encoded by RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: MGC119326, MGC119329, NR1F1, ROR1, ROR2, ROR3, RZRA, RZR-ALPHA
Protein Interaction Partner: COPS5,EP300,LMO3,MED1,MYOD1,NCOA2,NME1,NME2,NR0B1,PNRC1,PNRC2,PROX1,PSMC5,RORA,SMARCD3,ZXDC,EP300,MYOD1,NME1,PSMC5
Protein Size: 556 -
Molecular Weight
- 63 kDa
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Gene ID
- 6095
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NCBI Accession
- NM_134260, NP_599022
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UniProt
- P35398
Target
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