Runt-Related Transcription Factor 2 (RUNX2) Peptide
RUNX2
Host: Synthetic
BP, WB
Catalog No. ABIN983331
Quick Overview for Runt-Related Transcription Factor 2 (RUNX2) Peptide (ABIN983331)
Target
RUNX2
(Runt-Related Transcription Factor 2 (RUNX2))
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-RUNX2 antibody (Catalog #: ARP36679_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
-
Background
-
The RUNX2 gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis, acting as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD).
Protein Interaction Partner: RB1,AR,AXIN1,CBFB,CCNB1,CDK1,CEBPB,DVL2,EP300,ETS1,FOS,HDAC3,HDAC4,HDAC6,JUN,LEF1,MAP3K4,MSX2,MYST4,PRKCD,RB1,SMAD2,SMAD3,SMAD6,TAF1A,UBTF,XRCC5,XRCC6,YAP1,ETS1,FOS,HDAC3,HDAC4,HDAC6,JUN,LEF1,MSX2,MYST4,SMAD1,SMAD2,SMAD3,SMAD5,STUB1,THOC4,TLE1,YAP1
Protein Size: 589 -
Molecular Weight
- 64 kDa
-
Gene ID
- 860
-
UniProt
- Q5T802
Target
-
You are here:
