Retinoid X Receptor, gamma (RXRG) Peptide
RXRG
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN983358
Quick Overview for Retinoid X Receptor, gamma (RXRG) Peptide (ABIN983358)
Target
Retinoid X Receptor gamma (RXRG)
(Retinoid X Receptor, gamma (RXRG))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RXRG antibody (Catalog #: ARP45631_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Retinoid X Receptor, gamma (RXRG) peptide
RXRG Reactivity: Human, Cow, Dog, Pig, Mouse, Rat Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))
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Background
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RXRG encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. RXRG is expressed at significantly lower levels in non-small cell lung cancer cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: NR2B3, RXRC
Protein Interaction Partner: CAMK2B,CHGB,CREBBP,LRSAM1,MAP4,NCOA6,NCOR2,NR1H2,NR1H3,NR1H4,NR1I2,NR4A1,PNO1,PPARA,PPARD,PPARG,RARA,RARB,RARG,SRF,THRA,THRB,VDR,ITGB3BP,JUB,NR0B2,NR4A1,Nr0b2,PPARA,RARA,RPAP2,SRF
Protein Size: 463 -
Molecular Weight
- 51 kDa
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Gene ID
- 6258
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NCBI Accession
- NM_006917, NP_008848
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UniProt
- P48443
Target
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