Syndecan Binding Protein (Syntenin) (SDCBP) (Middle Region) Peptide
SDCBP
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all SDCBP products
- SDCBP (Syndecan Binding Protein (Syntenin) (SDCBP))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SDCBP antibody (Catalog #: ARP44536_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SDCBP (Syndecan Binding Protein (Syntenin) (SDCBP))
- Background
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SDCBP was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: MDA-9, ST1, SYCL, TACIP18
Protein Interaction Partner: EFNB2,EPHA7,NF2,NRXN1,SDC3,TGFA,CADM1,CD6,EFNB1,EFNB2,EPHB2,GRIA1,GRIA2,GRIA3,GRIA4,GRIK1,GRIK2,GRM3,IL5RA,NF2,NFASC,PTPRJ,RAB5A,RNF11,SDC1,SDC2,SDC4,SDCBP,SDCBP2,SLC6A5,SOX4,STX1A,TGFA,ULK1,WDR91,EFNB1,GRIA1,GRIA2,GRIA3,GRIA4,GRIK1,GRIK2,GRIK3,GRM3,GRM7,IL5RA,NF2,PTPRJ,RAB5A,SDC1,SDC2,SOX4,TRAF6,ULK1
Protein Size: 298 - Molecular Weight
- 32 kDa
- Gene ID
- 6386
- NCBI Accession
- NM_001007067, NP_001007068
- UniProt
- O00560
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