Selectin E (SELE) (N-Term) Peptide
SELE
Reactivity: Human
Host: Synthetic
BP, WB
Quick Overview for Selectin E (SELE) (N-Term) Peptide (ABIN983511)
Target
Selectin E/CD62e (SELE)
(Selectin E (SELE))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- WVWVGTQKPL TEEAKNWAPG EPNNRQKDED CVEIYIKREK DVGMWNDERC
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SELE Antibody(ARP59109_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Selectin E/CD62e (SELE) (Selectin E (SELE))
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Background
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The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
Alias Symbols: CD62E, ELAM, ELAM1, ESEL, LECAM2
Protein Interaction Partner: ACTN2,CD44,FLNA,GLG1,PLCG1,PTK2,PTPN11,PXN,SELL,SELPLG,SERPING1,VCL,GLG1,PLCG1,PTK2,PTPN11,PXN,SELL,SERPING1,TLN1
Protein Size: 610 -
Molecular Weight
- 64 kDa
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Gene ID
- 6401
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NCBI Accession
- NM_000450, NP_000441
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UniProt
- P16581
Target
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