Plasminogen Activator Inhibitor 1 (SERPINE1) (N-Term) Peptide
SERPINE1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN983585
Quick Overview for Plasminogen Activator Inhibitor 1 (SERPINE1) (N-Term) Peptide (ABIN983585)
Target
PAI1 (SERPINE1)
(Plasminogen Activator Inhibitor 1 (SERPINE1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- VAHLASDFGV RVFQQVAQAS KDRNVVFSPY GVASVLAMLQ LTTGGETQQQ
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SERPINE1 Antibody,. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
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Background
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SERPINE1 acts as 'bait' for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis.
Alias Symbols: PAI, PAI-1, PAI1, PLANH1
Protein Interaction Partner: ACTN4,ELANE,F2,IGFBP5,KLK2,KRT18,LRP1,LRP1B,LRP2,MMP3,ORM1,PLAT,PLAU,PLG,SERPINE1,UBQLN4,VTN,F2,IGFBP5,LRP1,ORM1,PLAT,PLAU,PLG,SERPINE1,VTN
Protein Size: 402 -
Molecular Weight
- 43 kDa
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Gene ID
- 5054
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NCBI Accession
- NM_000602, NP_000593
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UniProt
- P05121
Target
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