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SET Nuclear Oncogene (SET) (N-Term) Peptide

SET Reactivity: Human Host: Synthetic BP, IHC, WB, IP
Catalog No. ABIN983601

Quick Overview for SET Nuclear Oncogene (SET) (N-Term) Peptide (ABIN983601)

Target

SET/TAF-I (SET) (SET Nuclear Oncogene (SET))

Origin

Human

Source

  • 3
  • 1
Synthetic

Application

Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP)
  • Protein Region

    N-Term

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-SET antibody (Catalog #: ARP56542_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    SET/TAF-I (SET) (SET Nuclear Oncogene (SET))

    Background

    SET is a multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone binding. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activated DNase, NME1. In the course of cytotoxic T-lymphocyte (CTL)-indu

    Alias Symbols: 2PP2A, I2PP2A, IGAAD, PHAPII, TAF-IBETA, TAF-I, IPP2A2

    Protein Interaction Partner: ANP32A,APEX1,CDK5,CDK5R1,CDKN1A,ELAVL1,EP300,GZMA,HIST2H4A,HIST3H3,HMGB2,KLF5,MLL,NME1,PPP2CA,PPP2R1B,PTMA,RAC1,SET,SETBP1,SGOL1,TAF1A,THAP7,ANP32A,APEX1,CDK5R1,CDKN1A,DGKE,GZMA,HIST3H3,HIST4H4,HMGB2,KLF5,MEPCE,NME1,OTUD5,RGS20,SETBP1,TAF1A,THAP7,USP17L2,USP46,WDR48

    Protein Size: 277

    Molecular Weight

    32 kDa

    Gene ID

    6418

    NCBI Accession

    NM_003011, NP_003002

    UniProt

    B2RCX0
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