Splicing Factor 1 (SF1) (N-Term) Peptide
SF1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN983610
Quick Overview for Splicing Factor 1 (SF1) (N-Term) Peptide (ABIN983610)
Target
Splicing Factor 1 (SF1)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- LRTGDLGIPP NPEDRSPSPE PIYNSEGKRL NTREFRTRKK LEEERHNLIT
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SF1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Splicing Factor 1 (SF1)
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Background
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SF1 contains 1 CCHC-type zinc finger and 1 KH domain. SF1 is Necessary for the ATP-dependent first step of spliceosome assembly. It binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. SF1 may act as transcription repressor.
Alias Symbols: D11S636, ZFM1, ZNF162, BBP, MBBP
Protein Interaction Partner: BCL2,DDX17,EWSR1,FUS,PLSCR1,PRKG1,PRPF40A,RBPMS,TAF15,TCERG1,TRIM23,U2AF2,WWP2,APBB1,DDX17,EWSR1,FUS,GAS7,ITCH,NCOR2,PLSCR1,PRPF40A,RBPMS,SRC,TAF15,TCERG1,TRIM23,U2AF2,U2AF2,WBP4,WWP2,ZNF461
Protein Size: 639 -
Molecular Weight
- 68 kDa
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Gene ID
- 7536
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NCBI Accession
- NM_004630, NP_004621
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UniProt
- Q15637
Target
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