Splicing Factor 3b, Subunit 4, 49kDa (SF3B4) Peptide
SF3B4
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN983628
Quick Overview for Splicing Factor 3b, Subunit 4, 49kDa (SF3B4) Peptide (ABIN983628)
Target
SF3B4
(Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SF3B4 antibody (Catalog #: ARP40610_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))
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Background
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SF3B4 is one of four subunits of the splicing factor 3B. The protein cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
Alias Symbols: AFD1, Hsh49, SAP49, SF3b49
Protein Interaction Partner: SF3B2,BMPR1A,FAM115A,MAPK9,NCK2,SF3B2,SS18L1,STK19,SUMO4,TCERG1,BMPR1A,CDC5L,FAM115A,MAPK9,NCK2,RNU11,RNU12-2P,SF3A2,SF3B1,SF3B2,SMNDC1,SS18L1,TCERG1
Protein Size: 424 -
Molecular Weight
- 47 kDa
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Gene ID
- 10262
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NCBI Accession
- NM_005850, NP_005841
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UniProt
- Q15427
Target
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