Leucine-rich repeat protein SHOC-2 (SHOC2) (N-Term) Peptide
SHOC2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN983717
Quick Overview for Leucine-rich repeat protein SHOC-2 (SHOC2) (N-Term) Peptide (ABIN983717)
Target
SHoc2/Sur8 (SHOC2)
(Leucine-rich repeat protein SHOC-2 (SHOC2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- EKEAKASGGF GKESKEKEPK TKGKDAKDGK KDSSAAQPGV AFSVDNTIKR
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SHOC2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SHoc2/Sur8 (SHOC2) (Leucine-rich repeat protein SHOC-2 (SHOC2))
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Background
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This gene encodes a protein that consists almost entirely of leucine-rich repeats, a domain implicated in protein-protein interactions. The protein may function as a scaffold linking RAS to downstream signal transducers in the RAS/ERK MAP kinase signaling cascade. Mutations in this gene have been associated with Noonan-like syndrome with loose anagen hair.
Alias Symbols: FLJ60412, KIAA0862, SIAA0862, SOC-2, SOC2, SUR-8, SUR8
Protein Interaction Partner: ERBB2IP,HRAS,KRAS,NRAS,RAF1,HRAS,KRAS,MYC,RAF1,Shoc2,UBC
Protein Size: 582 -
Molecular Weight
- 65 kDa
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Gene ID
- 8036
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NCBI Accession
- NM_007373, NP_031399
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UniProt
- Q9UQ13
Target
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