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Sirtuin 3 (SIRT3) Peptide

SIRT3 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN983765

Quick Overview for Sirtuin 3 (SIRT3) Peptide (ABIN983765)

Target

SIRT3 (Sirtuin 3 (SIRT3))

Origin

Human

Source

  • 8
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Characteristics

    This is a synthetic peptide designed for use in combination with anti-SIRT3 antibody (Catalog #: ARP32388_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    SIRT3 (Sirtuin 3 (SIRT3))

    Background

    SIRT3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family.

    Alias Symbols: SIR2L3

    Protein Interaction Partner: DNM1L,PEX5,PEX5

    Protein Size: 399

    Molecular Weight

    44 kDa

    Gene ID

    23410

    NCBI Accession

    NM_012239, NP_036371

    UniProt

    Q9NTG7
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