High Affinity Choline Transporter (ChT) (Middle Region) Peptide
Quick Overview for High Affinity Choline Transporter (ChT) (Middle Region) Peptide (ABIN984035)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SLC5A7 antibody (Catalog #: ARP44024_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ChT (High Affinity Choline Transporter (ChT))
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Background
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Choline is a direct precursor of acetylcholine (ACh), a neurotransmitter of the central and peripheral nervous system that regulates a variety of autonomic, cognitive, and motor functions. SLC5A7 is a Na(+)- and Cl(-)- dependent high-affinity transporter that mediates the uptake of choline for acetylcholine synthesis in cholinergic neurons.Choline is a direct precursor of acetylcholine (ACh), a neurotransmitter of the central and peripheral nervous system that regulates a variety of autonomic, cognitive, and motor functions. SLC5A7 is a Na(+)- and Cl(-)- dependent high-affinity transporter that mediates the uptake of choline for acetylcholine synthesis in cholinergic neurons (Apparsundaram et al., 2000 [PubMed 11027560]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CHT, CHT1, MGC126299, MGC126300, hCHT
Protein Interaction Partner: PAWR,PAWR
Protein Size: 580 -
Molecular Weight
- 63 kDa
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Gene ID
- 60482
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NCBI Accession
- NM_021815, NP_068587
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UniProt
- Q9GZV3
Target
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