SRY (Sex Determining Region Y)-Box 2 (SOX2) Peptide
SOX2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN984266
Quick Overview for SRY (Sex Determining Region Y)-Box 2 (SOX2) Peptide (ABIN984266)
Target
SOX2
(SRY (Sex Determining Region Y)-Box 2 (SOX2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SOX2 antibody (Catalog #: ARP38232_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
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Background
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SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in this gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in this gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
Alias Symbols: ANOP3, MGC2413, MCOPS3
Protein Interaction Partner: NR5A1,POU2F1,POU5F1,PAX6,POU5F1
Protein Size: 317 -
Molecular Weight
- 34 kDa
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Gene ID
- 6657
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NCBI Accession
- NM_003106, NP_003097
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UniProt
- P48431
Target
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