Sperm Autoantigenic Protein 17 (SPA17) (N-Term) Peptide
SPA17
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all SPA17 products
- SPA17 (Sperm Autoantigenic Protein 17 (SPA17))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MSIPFSNTHY RIPQGFGNLL EGLTREILRE QPDNIPAFAA AYFESLLEKR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SPA17 Antibody(ARP53719_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SPA17 (Sperm Autoantigenic Protein 17 (SPA17))
- Background
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This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.
Alias Symbols: SP17, SP17-1, CT22
Protein Interaction Partner: AKAP3,ROPN1B,AKAP3
Protein Size: 151 - Molecular Weight
- 17 kDa
- Gene ID
- 53340
- NCBI Accession
- NM_017425, NP_059121
- UniProt
- Q15506
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