Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) (N-Term) Peptide
SPIC
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all SPIC products
- SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SPIC antibody (Catalog #: ARP39881_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))
- Background
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This protein Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression
Alias Symbols: MGC40611, SPI-C
Protein Size: 248 - Molecular Weight
- 29 kDa
- Gene ID
- 121599
- NCBI Accession
- NM_152323, NP_689536
- UniProt
- Q8N5J4
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