Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) (Middle Region) Peptide
SPIC
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN984347
Quick Overview for Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) (Middle Region) Peptide (ABIN984347)
Target
SPIC
(Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SPIC antibody (Catalog #: ARP39882_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))
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Background
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SPIC controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. SPIC is a transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. SPIC regulates VCAM1 gene expression.
Alias Symbols: MGC40611, SPI-C
Protein Size: 248 -
Molecular Weight
- 29 kDa
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Gene ID
- 121599
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NCBI Accession
- NM_152323, NP_689536
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UniProt
- Q8N5J4
Target
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